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Six Cycles of the Fasting Mimicking Diet: A Heart Doctor’s Experience

The science behind my success.

What is so special about the FMD? The science. After years of experimenting with the FMD in animal models and showing its benefits on metabolism and lifespan, Dr. Longo’s team analyzed the effects in a human clinical trial that was published earlier this year. One hundred healthy subjects participated in this study; half of them followed a Prolon FMD five days a month for three months, and the other half ate their usual diet. Profound differences were seen in terms of weight loss, visceral fat loss, drops in blood pressure, blood sugar, blood cholesterol, and markers of inflammation in the FMD group.

Even more profound was a drop of insulin-like growth factor 1 (IGF-1) — which is a biomarker for cancer growth — and an increase in stem cell production, which is a marker for regeneration of cells. In fact, the ProLon FMD program is marketed by Dr. Longo’s teams at USC as a program that promotes regenerative and rejuvenating changes, which is unique from all other data published for fasting programs. There are even provocative data suggesting that combining this FMD with cancer chemotherapy may lead to improved success and fewer side effects.

What I tell my patients about a fasting diet.

I advise my patients that if they want to achieve the published results, they will need to do three cycles chosen at times that they do not have conflicting events like weddings. After three consecutive months, I am confident some patients will choose to do the program monthly or every other month for long-term health optimization. I plan to continue the diet long-term, as the energy and weight loss I have observed has been so simple and something I want to maintain.

In my nearly 30 years of practicing cardiology and preventive medicine, I view the Prolon FMD as one of the greatest examples of translating years of peer-reviewed science — starting in yeast, then mice, and now humans — into a plan that almost anyone can adopt and benefit from. I thank Dr. Longo and his team who have set up this fasting program to benefit research programs at USC, and not for their own gain. In my opinion, the FMD is the best fasting approach and is the one most supported by scientific studies. It is also the scientific breakthrough of 2017.

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